Berberine hydrochloride

Waxay leedahay saameyn lid ku ah Escherichia coli, Escherichia coli, Diplococcus pneumoniae, Staphylococcus aureus, Streptococcus, Typhi iyo amoeba. Kiliinik ahaan, waxaa inta badan loo isticmaalaa in lagu baabi'iyo caabuqyada iyo bakteeriyada. Waxa kale oo la ogaaday in alaabtani ay leedahay saamayn anti-arrhythmic ah. Berberine waxay leedahay firfircoonida ka hortagga burooyinka ee vitro waxayna keeni kartaa dheecaanka unugyada B16; la mid ah cytarabinehydrochloridewaxay saameyn wanaagsan ku leedahay fayruuska.

Ujeedo
alkaloid isoquinoline. Qaaciddada molecular [C20H18NO4]+. Waxa kale oo loo yaqaan berberine. Waxay ka jirtaa dhir badan oo ku jira 10 genera iyo 4 qoys oo ay ku jiraan Berberidaceae. Berberine waxay soo dejin kartaa kiristaalo irbad huruud u eg oo laga soo qaatay ether-ka diethyl. Barta dhalaalka 145 ℃. Ku milmay biyaha, aan lagu milmi karin benzene, ether iyo chloroform. Berberine waa quaternary ammonium alkaloid, iyo milanka milixdeeda ee biyaha waa mid yar, tusaale ahaan, hydrochloride waa 1:500 iyo sulfate waa 1:30. Karistaanka berberine ee ka soo daatay biyaha ama ethanol-ka-diluteed waxay ka kooban yihiin 5.5 molecules oo biyo crystal ah; Haddii crystallized laga sameeyay chloroform, acetone ama benzene, waxay sidoo kale ka kooban yihiin unugyo dareere ah oo u dhigma. Berberine waxaa lagu daweyn karaa alkali kala duwan si loo helo saddex nooc oo kala duwan oo berberine ah: foomka ammonium quaternary, foomka aldehyde iyo foomka khamriga, kuwaas oo foomka ammonium quaternary uu yahay midka ugu xasilloon. Berberine waxay leedahay saameyn bakteeriyada hemolytic Streptococcus, Staphylococcus aureus, Neisseria gonorrhoeae, Freundii iyo Shigella dysenteriae, waxayna wanaajisaa phagocytosis ee unugyada dhiiga cad. Berberine hydrochloride (oo loo yaqaan berberine hydrochloride) ayaa si weyn loogu isticmaalaa daawaynta gastroenteritis, dysentery bacillary, iwm, waxayna sidoo kale saameyn gaar ah ku leedahay qaaxada, qandhada cas, qumanka degdega ah iyo caabuqyada neefsashada.

dawooyinka
farmashiyaha
Waxay leedahay bakteeriyada bakteeriyada ballaaran waxayna leedahay saameyn liddi ku ah bakteeriyada kala duwan ee Gram-positive iyo -negative bakteeriyada in vitro, oo ay ku jiraan hemolytic Streptococcus, Staphylococcus aureus, iyo Vibrio cholerae. Meningococci, Shigella dysenteriae, tiifowga bacilli, gawracatada bacilli, iwm waxay leeyihiin saameyn adag oo ka hortag ah. Waxay yihiin bacteriostatic at fiirsashada hoose iyo jeermis dilay at xad sare. Waxa kale oo ay leedahay saameyn ka hortag ah oo ku saabsan fayrasyada hargabka, amoeba, leptospira, iyo fangaska maqaarka qaarkood. Tijaabooyinka vitro-ga ayaa xaqiijiyay in berberine ay kor u qaadi karto awoodda fagocytic ee leukocytes iyo nidaamka reticuloendothelial beerka. Shigella dysenteriae, hemolytic Streptococcus, Staphylococcus aureus, iwm ayaa si fudud u adkaysan kara alaabtan. Ma jiro wax iska caabin ah oo u dhexeeya alaabtan iyo penicillin iyo streptomycin.

Farmashiyaha
nuugista afka oo liidata. Ka dib cirbadeynta, waxay si dhakhso ah u gashaa xubnaha iyo unugyada kala duwan, waxaana la ilaaliyaa xoojinta dhiigga muddo gaaban. U fiirsashada dhiigga ka dib duritaanka murqaha ayaa ka hooseeya diiradda ugu yar ee xakamaynta. Daawada ayaa si weyn loogu qaybiyaa, inta badan wadnaha, lafaha, sambabada iyo beerka. Wakhtiga haynta unugyadu waa gaaban yahay, oo qadar raadad ah ayaa hadhaya 24 saacadood ka dib. Daawooyinka intooda badan waa la dheefshiido oo laga tirtiraa jirka, wax ka yar 5% qiyaasta daawada ayaa laga soo saaraa qaabka asalka ah 48 saacadood gudahood.
Sida laga soo xigtay warbixinadii ugu dambeeyay, waxaa la rumeysan yahay in badeecadani ay yareyn karto tirada pili ee dusha bakteeriyada, ka hortagga bakteeriyada inay ku xirto unugyada aadanaha, waxayna leedahay saameyn daweyn ah. Alaabtani waxay sidoo kale saameyn ku leedahay Helicobacter waxayna yareyn kartaa gastritis, boogaha gastric iyo duodenal boogaha.

Naafo ah oo si taxadar leh loo isticmaalo
Inkasta oo loo isticmaali karo carruurta, waa ka mamnuuc carruurta leh gulukoosta-6-fosfate deficiency dehydrogenase la dhaxlo sababtoo ah alaabtani waxay keeni kartaa dhiig-yaraan hemolytic waxayna u horseedi kartaa cagaarshow.

Dareen-celinta xun
(1) Dareen-celinta xun ee afka waa naadir, oo leh lalabo, matag, finan iyo qandho daroogo, kuwaas oo baaba'a ka dib joojinta daawada.
(2) Duritaan ama faleebo laga qaato waxay sababi karaan falcelinno ay ka mid yihiin vasodilation, cadaadiska dhiigga oo hoos u dhaca, iyo niyad-jabka wadnaha. Xaaladaha daran, Aspen syndrome ayaa dhici karta, iyo xitaa dhimasho. Shiinaha ayaa ku dhawaaqay in la baabi'iyay cirbadaha kala duwan ee berberine hydrochloride.
Dad yar ayaa qaba calool xanuun fudud ama calool xanuun, calool istaag ama shuban.

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